Road to Ruin is the fourth studio album by American punk rock band the Ramones, released on September 22, 1978, through Sire Records as LP record, 8 track cartridge & audio cassette. It was the first Ramones album to feature new drummer Marky Ramone, who replaced Tommy Ramone. Tommy left the band due to low sales of previous albums as well as stress he experienced while touring; however, he stayed with the band to produce the album (credited as T. Erdelyi) with Ed Stasium. The artwork's concept was designed by Ramones fan Gus MacDonald and later modified by John Holmstrom to include Marky instead of Tommy. The album includes the well-known track "I Wanna Be Sedated".

The album incorporated musical elements that were less prominent in punk rock, such as heavy metal-influenced guitar solos and 1960s-style ballads. The songs on Road to Ruin are considered by some as an attempt to get the band more airplay. The album did not sell as well as the band had hoped, peaking at number 103 on the Billboard 200, more than 50 places behind its predecessor, Rocket to Russia. However, Road to Ruin lives on decades later as a fan favorite, as well as a popular album for them on Spotify. A decade after its release, a successful music video for "I Wanna Be Sedated" appeared in 1988; it is their second most-played song on Spotify. This album has had multiple re-releases with new work from producer Ed Stasium.